Disclaimer: These calculators and simulators have not been fully validated and are for entertainment purposes only. Not a substitute for professional medical judgment.

Alveolar Gas Equation & A-a Gradient

Input Parameters

Advanced (defaults shown)

Formulas

Alveolar Gas Equation:
PAO2 = FiO2 × (Patm − PH2O) − (PaCO2 / RQ)

A-a Gradient:
A-a = PAO2 − PaO2

Expected A-a Gradient (adults):
Expected = (Age / 4) + 4

PH2O = 47 mmHg at body temperature. Normal A-a gradient in pediatrics is typically < 10 mmHg on room air.

A-a Gradient Interpretation
< 10 mmHgNormal
10 – 20 mmHgMildly elevated
20 – 40 mmHgModerately elevated
≥ 40 mmHgSeverely elevated